The C-terminal domain of tyrosyl-tRNA synthetase contains major binding determinants for the tRNA.
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Which of the following amino acids can be used in place of lysine, arginine, and histidine to remove the electrostatic charge but retain the hydrophilic nature of the side chain?
Tyrosine is activated at an amino group with ATP to form tyrosyl adenylate.
The tRNA makes contact with the synthetase at only a single specific position.
Both the subunits of heterodimers are involved in tRNA binding.
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