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Tissue Engineering Mcqs

Q:

_____________ is the first process involved in Biomaterial-Tissue interaction.

A) Foreign Body Response B) Elongation
C) Adhesion D) Replication
 
Answer & Explanation Answer: A) Foreign Body Response

Explanation: All in all, the nature of the cooperation among biomaterials and tissues in the body can be portrayed by two primary procedures. The foreign body response (FBR), is particularly activated on account of an implantable gadget so as to shield the body from the remote material. Once the biomaterial gadget or platform is embedded in the body, a tissue/biomaterial interface straightforwardly structures and causes a progression of incendiary reactions.

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569
Q:

Which of the following is a characterization technique used to measure Young’s modulus of a biomaterial?

A) Tensile test B) Compression test
C) Three- and four-point bend test D) Calculation from the stress-strain curve
 
Answer & Explanation Answer: D) Calculation from the stress-strain curve

Explanation: Tensile test helps in measurement of tensile strength, Compression test helps in measurement of Compressive strength, three- and four-point bend test helps in measurement of flexural strength and calculations from stress-strain curve help in measurement of Young’s modulus.

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274
Q:

Constant stress test helps in measurement of ____________ for a biomaterial.

A) ductility B) toughness
C) creep D) fatigue
 
Answer & Explanation Answer: A) ductility

Explanation: Calculations from strength test help in measurement of Ductility, Single edge notched-beam Indirect measurement helps in measurement of Toughness, Constant stress test helps in measurement of Creep and Cyclic stress test help in measurement of Fatigue.

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271
Q:

What is the first step in Biomaterial-tissue interactions?

A) Cell Migration B) Adsorption of proteins
C) Cell Development D) Cell adhesion
 
Answer & Explanation Answer: D) Cell adhesion

Explanation: The initial phase in biomaterial–tissue connection is the underlying adsorption of proteins onto the outside of the biomaterial, which, in a mix with the physical and multiple properties of the surface, is thought to prompt ensuing cell practices, for example, bond, spreading and expansion.

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210
Q:

________ is the technique used to detect genetic disorders.

A) Preimplantation genetic diagnosis (PGD) B) Gene therapy
C) Cell therapy D) Proliferation
 
Answer & Explanation Answer: A) Preimplantation genetic diagnosis (PGD)

Explanation: New human ES cell lines were set up from developing embryos with a hereditary issue, which were identified during the act of preimplantation genetic diagnosis (PGD). These new cell lines may give a superb in vitro model for concentrates on the impacts that the hereditary transformations have on cell expansion and separation.

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192
Q:

Induced pluripotent stem cells are _____________ in nature thus minimizing the chances of immune rejection.

A) autologous B) proliferative
C) differentiating D) adherent
 
Answer & Explanation Answer: A) autologous

Explanation: The most outstanding kind of pluripotent stem cell is the embryonic stem cell. Be that as it may, since the age of embryonic stem cell includes pulverization (or possibly manipulation) of the pre-implantation organize incipient organism, there has been much contention encompassing their utilization.

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169
Q:

_________ link extracellular matrix to keratin intermediate filaments.

A) Integrins B) Cadherins
C) Immunoglobulins D) Selectins
 
Answer & Explanation Answer: A) Integrins

Explanation: In hemidesmosomes, integrins attach to ECM proteins called laminins in the basal lamina, which is the ECM secreted by the epithelial cells. Integrins link ECM to keratin intermediate filaments. Hemidesmosomes are important in maintaining the structural stability of epithelial cells by anchoring them together indirectly through the extracellular matrix.

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167
Q:

Scaffolds are built by adding layer by layer using a computer program in phase separation method.

A) TRUE B) FALSE
 
Answer & Explanation Answer: B) FALSE

Explanation: Complex shaped scaffolds are built by adding materials layer-by-layer as dictated by a computer program. Each layer represents a cross-section of the scaffold at a certain level.

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